How long does the drug stay in our body?
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Key takeaway: there is no single detection time. The window varies depending on the substance, sample type, frequency of use, test threshold, and screening context.
The detection time of a drug depends on the substance consumed, the type of sample used, the test threshold, frequency of use, metabolism, and the screening context. Results can vary greatly from person to person.
This comprehensive guide explains the differences between urine test, saliva test, blood test, and hair analysis, with the main known detection times for cannabis, cocaine, amphetamines, MDMA, opiates, GHB, ketamine, and benzodiazepines.
Often longer window, useful for detecting a recent or extended history depending on the substance.
Shorter window, suited for recent use, roadside checks, and high-risk posts.
Long history, often up to about 90 days depending on the length analyzed, but not well suited for very recent use.
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Detection times, differences between urine, saliva, blood, and hair, and key points for interpreting a screening result.
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Summary
- Quick answer: how long do drugs remain detectable?
- Urine, saliva, blood, hair: understanding the differences
- Complete detection time table
- Detection times in saliva
- Detection times in urine
- Detection times in blood
- Detection times in hair
- Factors influencing positivity duration
- Why results can vary between tests
- Roadside check, THC, CBD, and saliva test
- Workplace screening: framework and prevention
- Which tests to choose according to the need?
- Complete FAQ
Quick answer: there is no single duration
A drug can be detectable for a few hours, several days, weeks, or months depending on the test used. Generally, blood and saliva detect more recent use, urine often detects a wider window, and hair allows for detecting a longer history.
The durations given in this article are indicative benchmarks. They never guarantee that a person will test negative at a specific date or time.
Urine, saliva, blood, hair: understanding the differences
Not all tests look for exactly the same thing. A saliva test can target the active substance present in the mouth, a urine test often looks for metabolites eliminated by the body, blood measures a more recent presence, and hair can reflect a longer history.
Recent use
Saliva testing is quick, non-invasive, and suited for situations requiring immediate response: roadside checks, prevention before driving, sensitive posts, or field screening.
Recent or prolonged history
Urine testing is widely used because it is simple to perform and often detects metabolites for a longer duration than saliva.
Recent presence
Blood is more invasive and reserved for medical, toxicological, or official contexts. It can provide more direct information on recent presence.
Long history
Hair analysis can document older exposure but is poorly suited for detecting very recent use and requires specialized analysis.
Key point
A negative test does not always mean absolute absence of substance. The substance may be present below the detection threshold, already eliminated from the tested matrix, or not sought by the panel used.
Complete table of drug detection times
This table groups generally observed detection times. They should be interpreted with caution: frequency of use, quantity, administration route, metabolism, test threshold, and sample quality can strongly affect the result.
| Substance | Saliva | Urine | Blood | Hair | Key points |
|---|---|---|---|---|---|
| Cannabis / THC | Occasional use: 6 to 8 hours; regular use: up to 24 hours; heavy use: possibly longer. | Occasional use: 3 to 5 days; regular use: 30 to 70 days. | THC: 2 to 8 hours with occasional use; THC-COOH up to 72 hours; longer with heavy use. | Often up to about 90 days depending on the length analyzed. | THC is fat-soluble and can remain detectable longer in regular users. |
| Cocaine / crack | About 24 hours; up to 48 hours with regular use. | 2 to 4 days; up to 10 to 14 days with prolonged daily heavy use. | A few hours, generally less than 24 hours. | Possible history via hair analysis. | Benzoylecgonine is often the marker sought. |
| Amphetamines | Up to about 50 hours. | Up to 4 days. | 2 to 4 days. | Possible history via hair analysis. | The window depends on the threshold, dose, and frequency. |
| Methamphetamines | Up to about 50 hours. | More than 7 days. | 2 to 4 days. | Possible history via hair analysis. | Panels can distinguish AMP and MET. |
| MDMA / ecstasy | Up to 12 hours according to Drogues Info Service; up to 50 hours according to some amphetamine panels. | Up to 72 hours. | Up to 8 hours. | Possible history via hair analysis. | Thresholds and the molecule sought strongly influence the duration. |
| Heroin / morphine / opiates | 12 to 24 hours; codeine: 9 to 12 hours. | 48 to 72 hours; codeine: 24 to 48 hours. | Up to 24 hours; codeine: up to 8 hours. | Possible history via hair analysis. | Some medications containing morphine or codeine can influence the opiate result. |
| Methadone | Not found in standard road saliva tests according to Drogues Info Service; some specific tests may detect it. | 3 to 7 days. | Up to 48 hours. | Possible history via hair analysis. | A test explicitly including methadone must be used. |
| Buprenorphine | Not found in standard road saliva tests according to Drogues Info Service; some specific tests may detect it. | 1 to 2 days. | Up to 8 hours. | Possible history via hair analysis. | A test adapted to the marker sought is required. |
| Benzodiazepines | Variable depending on tests; standard road tests do not systematically detect them. | 2 days to 6 weeks depending on molecule, dose, and duration of use. | 6 to 8 hours according to Drogues Info Service. | Possible history via hair analysis. | Highly variable family: short, intermediate, or long half-life. |
| GHB / GBL | Very short; rarely tested by classic saliva tests. | About 10 hours, sometimes less than 12 hours. | About 6 hours, sometimes only a few hours. | Specialized analysis possible. | Very short window: act quickly if chemical submission is suspected. |
| Ketamine | Not detected in standard road checks according to Drogues Info Service; specific tests required. | 2 to 3 days. | About 1 day. | Specialized analysis possible. | Important for risk prevention and chemical submission, but requires a suitable device. |
| LSD | Variable depending on panels; rarely tested by common rapid tests. | 1 to 2 days. | A few hours. | Specialized analysis possible. | Substance rarely included in standard rapid tests. |
Detection times in saliva
The drug saliva test is especially useful for detecting recent use. It is quick, non-invasive, and often used in road safety prevention, field checks, or security at sensitive posts.
What Drugdiag® Saliva instructions say
Drugdiag® saliva tests are qualitative immunochromatographic tests. They do not provide an exact concentration: they indicate whether the substance tested is detected above or below the test's detection threshold.
| AMA Prévention saliva test | Substances tested | Indicated thresholds | Recommended use |
|---|---|---|---|
| Drugdiag® Saliva THC | THC cannabis | THC: 15 ng/mL | Preventive self-monitoring and targeted cannabis screening. |
| Drugdiag® Saliva 5+ | COC, AMP, OPI, MET, THC | COC 10; AMP 50; OPI 10; MET 50; THC 15 ng/mL. | Multi-drug screening of main families. |
| Drugdiag® Saliva 6+ | COC, AMP, OPI, MET, THC, BZO depending on reference. | THC 15; BZO 30; other thresholds depending on reference. | Expanded screening, especially for benzodiazepines depending on the model. |
| Drugdiag® Saliva 5+ Innovation | COC, AMP, OPI, MET, THC | COC 10; AMP 50; OPI 10; MET 50; THC 15 ng/mL. | Professional campaigns, fieldwork, easy sampling. |
Do not put anything in the mouth before the test
Instructions require not putting anything in the mouth for at least 10 minutes before the test: no food, no drink, no chewing gum, and no tobacco. This step reduces the risk of sampling and interpretation errors.
Detection times in urine
The urine drug test is often used when a longer detection window is needed. It generally looks for metabolites eliminated by the body, which explains why some substances remain positive longer in urine than in saliva or blood.
Wider window
Urine is suitable for monitoring, internal protocols, family or professional prevention, and multi-drug panels.
Risk of falsification
Urine sampling requires a more controlled protocol. Cup formats with temperature control help limit some substitution or dilution attempts.
For companies, healthcare professionals, or individuals seeking a broad panel, Drugdiag® urine tests may be more suitable than saliva tests, especially for certain new synthetic drugs or for a longer detection window.
Detection times in blood
Blood is a more invasive matrix, used in medical, toxicological, or official contexts. It is better suited for assessing recent presence, but its detection window is generally shorter than that of urine for many substances.
Why blood is different
The presence of a substance in the blood can decrease rapidly, while its metabolites remain detectable longer in urine. This is why the same individual can show different results depending on the matrix analyzed.
Detection times in hair
Hair analysis allows for documenting a longer history. It is often used to detect repeated or past exposure, but it is not the most relevant method for detecting very recent consumption.
Long history
Hair analysis can reflect several weeks or months depending on the length of hair analyzed.
Not for immediate detection
Hair is not the best choice to assess very recent use. Laboratory protocols, sampling type, and risk of external contamination must also be considered.
Factors influencing positivity duration
The duration a drug remains detectable depends not only on the substance but also on the person, the test, and the sampling context.
Frequency and quantity
A single use can disappear faster than regular or intensive use. Cannabis is the clearest example.
Individual profile
Weight, metabolism, health status, hydration, fat mass, and certain medications can influence elimination.
Threshold and matrix
A saliva, urine, blood, or hair test does not always detect the same molecule or at the same threshold.
- The administration route can change the speed of appearance and elimination.
- Regular use often extends the detection window.
- A negative result may simply mean the concentration is below the test threshold.
- A positive rapid result sometimes needs confirmation by laboratory methods depending on the context.
- A test not suited to the substance sought can give a false sense of security.
Why results can vary between tests
Two tests performed on the same person can give different results if they do not detect the same substance, family, metabolite, or if they do not have the same detection threshold.
Saliva vs urine
A THC saliva test mainly detects THC present in saliva. A urine test rather detects THC-COOH, the main cannabis metabolite. Detection windows are therefore not the same.
Broad family
A positive “opioids” result can be linked to several substances in the same family, including certain medications like morphine or codeine depending on the context.
Quick result = indicative result
Rapid tests are screening tools. In cases of medical, disciplinary, judicial, or professional stakes, confirmation by laboratory methods may be necessary.
Roadside check, THC, CBD, and saliva test
During a roadside check, saliva screening is used to detect drug use. In France, the decree of December 13, 2016, sets reference saliva thresholds for cannabinoid, amphetamine, cocaine, and opioid families.
| Family | Substance | Saliva reference threshold | Urine reference threshold |
|---|---|---|---|
| Cannabinoids | THC / THC-COOH depending on matrix | THC: 15 ng/mL saliva | THC-COOH: 50 ng/mL urine |
| Amphetamines | Amphetamine, methamphetamine, MDMA | 50 ng/mL saliva | 1,000 ng/mL urine |
| Cocainics | Cocaine or benzoylecgonine | 10 ng/mL saliva | 300 ng/mL urine |
| Opiates | Morphine, 6-MAM | 10 ng/mL saliva | Morphine: 300 ng/mL urine |
CBD and risk of THC positivity
Pure CBD is not targeted by a THC test. However, some CBD products may contain residual traces of THC. With regular consumption or insufficiently controlled products, a positive THC result remains possible.
A self-test does not grant driving authorization
A self-administered saliva test can help assess a situation but does not replace official procedures and does not guarantee legal fitness to drive.
Workplace screening: framework and prevention
In companies, screening should not be considered as generalized surveillance. It must be part of a prevention approach, especially for high-risk positions: driving, handling, safety, dangerous machinery, transport, isolated work, or activities requiring high vigilance.
The INRS reminds that the use of saliva drug tests must be regulated, included in internal regulations, reserved for positions with particular danger, not systematic, and accompanied by the possibility of medical counter-expertise.
- Identify high-risk positions and justify the use of screening.
- Include the procedures in the internal regulations or applicable internal framework.
- Inform employees and respect confidentiality.
- Train the people conducting the tests.
- Plan the procedure in case of positive, negative, invalid, or disputed results.
Which tests to choose according to the need?
AMA Prévention offers Drugdiag® saliva and urine tests adapted to different contexts: road safety, self-testing, workplace screening, monitoring, professional protocol, or multi-drug research.
THC saliva test
To detect recent presence of THC in saliva. Suitable for preventive self-testing and targeted cannabis screening.
5-drug saliva test
To detect the main families: THC, cocaine, amphetamines, methamphetamines, and opiates according to the device.
6-drug saliva test
For extended saliva coverage, including benzodiazepines according to the product reference.
Drugdiag® urine tests
For a longer detection window, a broad panel, or a professional monitoring protocol.
Shipping and support
24h shipping with DPD for eligible orders and Colissimo 48/72h for other orders, subject to stock availability. For professional needs, AMA Prévention can guide you to the most suitable test: saliva, urine, cup, cassette, THC test, multi-drug, or new synthetic drugs.
Complete FAQ on drug detection times
How long does cannabis remain detectable?
In saliva, THC can be detectable 6 to 8 hours with occasional use, up to 24 hours with regular use, and sometimes longer with intensive use. In urine, Drogues Info Service indicates 3 to 5 days with occasional use and 30 to 70 days with regular use.
Which test detects drugs for the longest time?
Hair analysis generally offers the longest detection window. Urine follows for many substances. Saliva and blood are more suited to recent use.
Why can a saliva test be negative while a urine test is positive?
Because the two tests do not always look for the same thing. Saliva detects more recent use, while urine can detect metabolites eliminated longer by the body.
How long does cocaine remain detectable?
Cocaine can be detectable for about 24 hours in saliva, up to 48 hours with regular use, 2 to 4 days in urine, and a few hours in blood according to Drogues Info Service.
How long does MDMA remain detectable?
Drogues Info Service indicates up to 12 hours in saliva, up to 72 hours in urine, and up to 8 hours in blood. The duration can vary depending on the product, dose, threshold, and frequency of use.
How long does GHB remain detectable?
GHB has a very short detection window. Drogues Info Service indicates about 10 hours in urine and about 6 hours in blood. In case of suspected chemical submission, it is essential to act quickly and contact the appropriate services.
Can a CBD product cause a positive THC test?
Yes, if the CBD product contains residual traces of THC or if consumption is repeated. Pure CBD is not targeted by a THC test, but the THC present in some products can be detected.
Can the elimination of a drug be accelerated?
There is no reliable method to guarantee a negative result on a specific date. Durations depend on many factors: substance, dose, frequency, metabolism, matrix, test threshold, and physiological state.
Which test to choose before getting back on the road?
To detect recent consumption, the saliva test is generally the most relevant. However, it does not provide legal authorization to drive and does not replace official controls.
Where to buy a reliable screening test?
AMA Prévention offers Drugdiag® saliva and urine tests for individuals, companies, healthcare professionals, and prevention actors. The choice depends on the substance sought, the desired detection window, and the context of use.
Official sources and useful references
The indicated durations remain guidelines. For further details, consult the following sources:
- Drogues Info Service — Table of positivity durations
- Légifrance — Decree of December 13, 2016, on drug screening
- INRS — Addictions, regulation, and workplace screening
- Technical datasheets Toda Pharma Drugdiag® Saliva: Saliva THC, Saliva 5+, Saliva 6+, and Saliva 5+ Innovation.
Conclusion
The detection window for drugs varies depending on the substance, the test used, and the person's profile. Saliva and blood are mainly useful for recent consumption; urine often covers a longer period; hair allows exploration of an older history.
For a serious prevention approach, the choice of test must always correspond to the substance sought, the context, the assumed time since intake, and the expected level of reliability.
B-SAFE scientific validation
The B-SAFE project, a drug detector pen for drinks, is validated and supported by Professor Jean-Claude Alvarez, toxicologist, professor of pharmacology-toxicology, and director of the toxicology laboratory at CHU Raymond-Poincaré/AP-HP in Garches.
A leading authority in toxicology, he is associated with the reference work conducted in France on psychoactive substances and chemical submission, in a national ecosystem also supported in public debate by voices such as Sandrine Josso and Caroline Darian.
This validation strengthens B-SAFE's technological positioning and the accuracy of its detection for drug prevention in drinks. Discover the B-SAFE product sheet.
